Nūhou

Ua ʻike mua ʻia ʻo XE ma UK ma Pepeluali 15 o kēia makahiki.

Ma mua o XE, pono mākou e aʻo i kekahi ʻike kumu e pili ana i ka COVID-19. He maʻalahi ke ʻano o ka COVID-19, ʻo ia hoʻi, nā nucleic acids me kahi pūpū protein ma waho. Ua hoʻokaʻawale ʻia ka protein COVID-19 i ʻelua ʻāpana: structure protein a me ka non structural protein (NSP). ʻO nā pūmua kūkulu hale nā ​​ʻano ʻehā o ka spike protein S, envelop protein E, membrane protein M a me ka nucleocapsid protein N. ʻO ia nā protein e pono ai e hana i nā ʻāpana virus. No nā pūmua non structural, ʻoi aku ma mua o hoʻokahi kakini. ʻO lākou nā protein i hoʻopaʻa ʻia e ka genome virus a loaʻa kekahi mau hana i ke kaʻina hana o ka hoʻopiʻi hou ʻana, akā ʻaʻole e hoʻopaʻa i nā ʻāpana virus.

ʻO kekahi o nā kaʻina koʻikoʻi koʻikoʻi no ka ʻike ʻana i ka waikawa nucleic (RT-PCR) ʻo ia ka conservative ORF1 a/b māhele o COVID-19. ʻAʻole pili ka hoʻololi ʻana o nā ʻano like ʻole i ka ʻike ʻana i ka waika nucleic.

E like me ka maʻi RNA, hiki i ka COVID-19 ke hoʻololi i ka mutation, akā ʻo ka hapa nui o nā mutations he mea ʻole. E loaʻa i kekahi o lākou nā hopena maikaʻi ʻole. Hiki i kekahi mau mutations ke hoʻonui i ko lākou hiki ke pakele i ka infectious, pathogenic a immune paha.

Ua hōʻike ʻia nā hopena o ka hoʻopili ʻana i ke ʻano he ʻoi aku ka ORF1a o XE mai ka Omicron's BA.1, aʻo ke koena mai ka Omicron's BA.2, ʻoi aku ka nui o nā genes o ka ʻāpana protein S - ʻo ia hoʻi, ʻoi aku ka kokoke o kāna mau hiʻohiʻona i ka BA.2 .

ʻO BA.2 ka maʻi maʻi lele loa i loaʻa i nā makahiki i hala iho nei. No ka hopena o ka maʻi maʻi, nānā mākou iā R0, ʻo ia hoʻi, hiki i kahi mea maʻi ke hoʻopili i kekahi mau kānaka me ka ʻole o ka pale a me ka pale. ʻO ke kiʻekiʻe o ka R0, ʻoi aku ka nui o ka infectivity.

Ua hōʻike ʻia nā ʻikepili mua i ʻoi aku ka kiʻekiʻe o ka ulu ʻana o ka XE ma mua o ka BA.2 i hoʻonui ʻia e 10%, akā ua hōʻike ʻia nā ʻikepili ma hope ʻaʻole paʻa kēia kuhi. I kēia manawa, ʻaʻole hiki ke hoʻoholo ʻia ʻo kāna ulu ulu kiʻekiʻe ka pono i lawe ʻia e ka hoʻoponopono hou ʻana.

Ua manaʻo mua ʻia he ʻoi aku ka maikaʻi o nā ʻano ʻokoʻa nui e hiki mai ana ma mua o ka BA.2 o kēia manawa, a he paʻakikī ke wānana pololei i ka loli ʻana o kona ʻona (e hoʻonui a emi paha). I kēia manawa, ʻaʻole nui ka helu o kēia mau ʻano hou. ʻAʻole hiki ke huki i ka hopena inā paha e ulu kekahi o lākou i mau ʻano nui. Pono e nānā pono. No ka poʻe maʻamau, ʻaʻohe pono e hopohopo i kēia manawa. E alo i kēia mau BA.2 a i ʻole nā ​​ʻano like ʻole recombinant, koʻikoʻi loa ka hoʻopaʻa ʻana.

Ma ke alo o ka BA me ka hiki ke pakele i ka pale kino 2. I ka hihia o ka ma'i ma'amau ('elua doses), ua ho'emi nui 'ia ka helu kūpono o nā lā'au lapa'au 'elua i ho'ohana 'ia ma Hong Kong no ka pale 'ana i ka ma'i ma'i, akā na'e, loa'a ka ikaika. hopena i ka pale ʻana i ka maʻi nui a me ka make. Ma hope o ke kolu o ka lāʻau lapaʻau, ua hoʻomaikaʻi maikaʻi ʻia ka pale.