Haufinyane tjena, Tsamaiso ea Lijo le Lithethefatsi ea Naha ea Chaena (SFDA) e amohetse semmuso ts'ebeliso ea papatso ea dijocimab (PCSK-9 Monoclonal antibody e entsoeng ke INNOVENT BIOLOGICS,INC), INC bakeng sa kalafo ea hypercholesterolemia ea mantlha (ho kenyeletsoa heterozygous family hypercholesterolemia le non-family hypercholesterolemia). hypercholesterolemia) le dyslipidemia e tsoakiloeng. Ena ke inhibitor ea pele ea PCSK-9 e iketselitseng ho etsa kopo ea ho bapatsa naheng ea China.
Tafolecimab ke lithethefatsi tse ncha tsa biologic tse ikemetseng tse entsoeng ke INNOVENT BIOLOGICS, INC. IgG2 human monoclonal antibody ka ho khetheha e tlama PCSK-9 ho eketsa maemo a LDLR ka ho fokotsa PCSK-9-mediated endocytosis, kahoo e eketsa ho felisoa ha LDL-C le ho fokotsa maemo a LDL-C.
Lilemong tsa morao tjena, ho ata ha dyslipidemia ho eketsehile haholo Chaena. Ho ata ha lefu la dyslipidemia le hypercholesterolemia ho batho ba baholo ke 40.4% le 26.3% ka ho latellana. Ho ea ka tlaleho ea 2020 ea Cardiovascular Health and Diseases in China, kalafo le taolo ea lefu la dyslipidemia ho batho ba baholo li ntse li le maemong a tlase, mme sekhahla sa ho latela LDL-C sa bakuli ba dyslipidemia ha se khotsofatse le ho feta.
Pejana, li-statins e ne e le pheko ea mantlha ea hypercholesterolemia Chaena, empa bakuli ba bangata ba ne ba ntse ba hloleha ho fihlela sepheo sa kalafo sa phokotso ea LDL-C kamora kalafo. Papatso ea PCSK-9 e tlisitse katleho e ntle ho bakuli.
Ho romelloa ha thekisocimab ho tsoa ho INNOVENT BIOLOGICS, INC ho ipapisitse le liphetho tsa liteko tse tharo tsa bongaka tse ngolisitsoeng molemong oa demokrasi, E na le boemo bo botle ba polokeho ka kakaretso, bo ts'oanang le litšobotsi tsa polokeho ea lihlahisoa tse rekisitsoeng, 'me e fihletse nako e telele (libeke tse ling le tse ling tse 6) tsa tsamaiso. Liphetho tsa thuto ea CREDIT-2 li ile tsa amoheloa ke Seboka sa Selemo le Selemo sa 2022 sa American College of Cardiology (ACC) e le ntho e sa utloahaleng le e phatlalalitsoeng inthaneteng.
Haeba kopo e amohetsoe, e tla senya nako ea PCSK-9, Chaena e tla fetoha naha ea bone ho ba le PCSK-9 ka mor'a United States (Amgen), France (Sanofi) le Switzerland (Novartis).
Nako ea poso: Jul-04-2022