I-BSE izisa impembelelo enzulu kwishishini leSixhobo sezoNyango. Ayisiyiyo iKhomishoni yaseYurophu kuphela, kodwa iOstreliya kunye namanye amazwe aseAsia aphakamisa ibha yesixhobo sonyango esiqulathe okanye esenziwe ngumthombo wezilwanyana, esiphantse savala umnyango. Umzi-mveliso kufuneka ucinge ngokuthatha indawo yezixhobo zonyango ezifumaneka ngoku kwizilwanyana ngezinto ezintsha zokwenziwa. I-Plain Catgut enesidingo esikhulu semarike yokutshintsha emva kokuvalwa kweYurophu, phantsi kwale meko, iPoly(glycolide-co-caprolactone) (PGA-PCL) (75% -25%) , ukubhala okufutshane njenge-PGCL, yaphuhliswa njengokuba ukusebenza okuphezulu kokhuseleko yi-hydrolysis engcono kakhulu kuneCatgut yi-Enzymolysis.