Ukuhlinza Sutures
Ukuhlinza amaSutures abalulekile ekuvaleni amanxeba, anamandla okusebenzisa amandla amakhulu kunezinto zokunamathisela izicubu nokusheshisa inqubo yokuphulukisa yemvelo. Ziningi izinto ezisetshenziswayo zokuhlinza ezamukelwe le njongo - njengamapulasitiki awonakaliswayo futhi angonakali, amaphrotheni asuselwa kubhayoloji, nezinsimbi - kodwa ukusebenza kwawo kukhawulelwe ukuqina kwawo. Izinto ezivamile ze-suture zingabangela ukungakhululeki, ukuvuvukala nokuphulukiswa okuphazamisekile, phakathi kwezinye izinkinga zangemva kokuhlinzwa.
Emzamweni wokuxazulula le nkinga, abacwaningi abavela eMontreal basungule izindlela zokuhlinza zejeli eziqinile (TGS) eziphefumulelwe umthambo womuntu.
Lawa ma-suture esizukulwane esilandelayo aqukethe imvilophu yejeli eshelelayo, kodwa eqinile, elingisa ukwakheka kwezicubu ezithambile ezixhumeneyo. Ekuhloleni ijeli eqinile (TGS) sutures yokuhlinzwa, abacwaningi bathola ukuthi indawo yejeli ecishe ingabi nakhubaza inciphise umonakalo ovame ukudalwa ukuthungwa kwendabuko.
Izindlela zokuhlinza ezivamile sezinamakhulu eminyaka zikhona futhi zisetshenziselwa ukubamba amanxeba ndawonye kuze kuqedwe inqubo yokuphola. Kodwa awakulungele neze ukulungisa izicubu. Imicu eqinile ingasika futhi ilimaze izicubu ezivele zintekenteke, okuholela ekuphathekeni kabi kanye nezinkinga zangemva kokuhlinzwa.
Ngokusho kwabacwaningi, ingxenye yenkinga nge-sutures evamile ukungafani phakathi kwezicubu zethu ezithambile kanye nokuqina kwama-sutures agubha ngokumelene nokuxhumana kwezicubu. Inyuvesi yaseMcGill kanye nethimba le-INRS Énergie Matériaux Télécommunications Research Center babhekane nale nkinga ngokwakha ubuchwepheshe obusha obulingisa ubukhenikha bemisipha.
Igqugquzelwe Imisipha Yomuntu
Ukuze kubhekwane nale nkinga, leli qembu lenze ubuchwepheshe obusha obulingisa izinsimbi zamathenda. “Umklamo wethu ugqugquzelwe umzimba womuntu, i-endotenon sheath, eqinile futhi eqinile ngenxa yesakhiwo sayo esinenethiwekhi ekabili.
Ihlanganisa imicu ye-collagen ngenkathi inethiwekhi yayo ye-elastin iyiqinisa,” kusho umbhali oholayo uZhenwei Ma, ongumfundi we-PhD ngaphansi kokuqondisa kukaProfesa onguMsizi uJianyu Li waseMcGill University.
I-endotenon sheath yakha indawo eshelelayo ukuze kuncishiswe ukungqubuzana nezicubu ezizungezile futhi iphinde ilethe izinto zokulungisa izicubu ekulimaleni kwe-tendon, okuhlanganisa amaseli nemithambo yegazi nokuthuthwa kwabantu abaningi kanye nokulungisa ithoni.
Izinsimbi zokuhlinza ezine-gel sheathed (TGS) zingakhiwa ukuze zinikeze umuthi womuntu siqu ngokusekelwe ezidingweni zesiguli, kusho abacwaningi.
Next Generation Suture Materials
I-McGill University sutures iqukethe i-suture edumile yezentengiselwano eboshwe ngaphakathi kwemvilophu yejeli elingisa lesi sigqoko. I-tough gel sheathed (TGS) sutures yokuhlinza ingenziwa ifike ku-15cm ubude futhi ingamiswa iqhwa ukuze igcinwe isikhathi eside.
Besebenzisa kuqala isikhumba sengulube bese kuba imodeli yegundane, abacwaningi babonise ukuthi zingasetshenziselwa ukuthungwa okujwayelekile kwamafindo namafindo futhi ziyasebenza ekuvaleni kwesilonda ngaphandle kokubangela ukutheleleka.
Izindwangu zokuhlinza eziqinile zejeli (TGS) - ngokunye ukuhambisana namashethi e-endotenon - nazo zingaklanywa ukuhlinzeka ngokwelashwa kwesilonda komuntu siqu.
Ukwelashwa Kwenxeba Okuqondene Nakho
Abacwaningi babonise lesi simiso ngokulayisha ama-sutures nge-antibacterial compound, i-pH ezwa ama-microparticles, izidakamizwa kanye ne-fluorescent nanoparticles yokulwa nokutheleleka, ukuqapha umbhede wamanxeba, ukulethwa kwezidakamizwa kanye nezicelo ze-bioimaging.
“Lobu buchwepheshe buhlinzeka ngethuluzi elihlukahlukene lokulawula amanxeba okuthuthukile. Sikholelwa ukuthi ingase isetshenziselwe ukuletha izidakamizwa, ukuvimbela izifo, noma ngisho nokuqapha amanxeba ngezithombe eziseduze ne-infrared,” kusho uLi woMnyango Wezobunjiniyela Bemishini.
"Ikhono lokuqapha amanxeba endaweni futhi ulungise isu lokwelapha ukuze ululame kangcono liyisiqondiso esijabulisayo sokuhlola," kusho uLi, ophinde abe nguSihlalo Wocwaningo lwaseCanada ku-Biomaterials and Musculoskeletal Health.
Izinkomba Eziyinhloko:
1. Inyuvesi yaseMcGill
2. Umgodla wejeli oqinile we-Bioinspired wokusebenza okuqinile nokuguquguqukayo kwendawo. UZhenwei Ma et. al. Intuthuko Yesayensi, 2021; 7 (15): eabc3012 DOI: 10.1126/sciadv.abc3012
Isikhathi sokuthumela: Apr-02-2022